Linear and Differential Ion Mobility Separations of Middle-Down Proteoforms

Comprehensive characterization of proteomes comprising the same proteins with distinct post-translational modifications (PTMs) is a staggering challenge. Many such proteoforms are isomers (localization variants) that require separation followed by top-down or middle-down mass-spectrometric analyses,...

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Bibliografske podrobnosti
izdano v:Anal Chem
Main Authors: Garabedian, Alyssa, Baird, Matthew, Porter, Jacob, Jeanne Dit Fouque, Kevin, Shliaha, Pavel V., Jensen, Ole N., Williams, Todd D., Fernandez-Lima, Francisco, Shvartsburg, Alexandre
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366606/
https://ncbi.nlm.nih.gov/pubmed/29359922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b05224
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