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Ion Mobility Separation of Variant Histone Tails Extending to the “Middle-down” Range

Differential ion mobility spectrometry (FAIMS) can baseline-resolve multiple variants of post-translationally modified peptides extending to the 3 - 4 kDa range, which differ in the localization of a PTM as small as acetylation. Essentially orthogonal separations for different charge states expand t...

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Bibliografske podrobnosti
Main Authors: Shvartsburg, Alexandre A., Zheng, Yupeng, Smith, Richard D., Kelleher, Neil L.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353003/
https://ncbi.nlm.nih.gov/pubmed/22559289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac300612y
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