Characterization of Complete Histone Tail Proteoforms Using Differential Ion Mobility Spectrometry

[Image: see text] Histone proteins are subject to dynamic post-translational modifications (PTMs) that cooperatively modulate the chromatin structure and function. Nearly all functional PTMs are found on the N-terminal histone domains (tails) of ∼50 residues protruding from the nucleosome core. Usin...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Shliaha, Pavel V., Baird, Matthew A., Nielsen, Mogens M., Gorshkov, Vladimir, Bowman, Andrew P., Kaszycki, Julia L., Jensen, Ole N., Shvartsburg, Alexandre A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436587/
https://ncbi.nlm.nih.gov/pubmed/28406606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b00379
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