Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer

BACKGROUND: Genome-wide association studies (GWAS) are widely used to map genomic regions contributing to lung cancer (LC) susceptibility but they typically do not identify the precise disease-causing genes/variants. To unveil the inherited causal LC variants, we performed focused exome sequencing a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Thorac Oncol
Prif Awduron: Liu, Yanhong, Lusk, Christine M., Cho, Michael H., Silverman, Edwin K., Qiao, Dandi, Zhang, Ruyang, Scheurer, Michael E., Kheradmand, Farrah, Wheeler, David A., Tsavachidis, Spiridon, Armstrong, Georgina, Zhu, Dakai, Wistuba, Ignacio I., Chow, Chi-Wan B., Behrens, Carmen, Pikielny, Claudio W., Neslund-Dudas, Christine, Pinney, Susan M., Anderson, Marshall, Kupert, Elena, Bailey-Wilson, Joan, Gaba, Colette, Mandal, Diptasri, You, Ming, de Andrade, Mariza, Yang, Ping, Field, John K., Liloglou, Triantafillos, Davies, Michael, Lissowska, Jolanta, Swiatkowska, Beata, Zaridze, David, Mukeriya, Anush, Janout, Vladimir, Holcatova, Ivana, Mates, Dana, Milosavljevic, Sasa, Scelo, Ghislaine, Brennan, Paul, McKay, James, Liu, Geoffrey, Hung, Rayjean J., Christiani, David C., Schwartz, Ann G., Amos, Christopher I, Spitz, Margaret R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366341/
https://ncbi.nlm.nih.gov/pubmed/29981437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2018.06.016
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