Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer

BACKGROUND: Genome-wide association studies (GWAS) are widely used to map genomic regions contributing to lung cancer (LC) susceptibility but they typically do not identify the precise disease-causing genes/variants. To unveil the inherited causal LC variants, we performed focused exome sequencing a...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Liu, Yanhong, Lusk, Christine M., Cho, Michael H., Silverman, Edwin K., Qiao, Dandi, Zhang, Ruyang, Scheurer, Michael E., Kheradmand, Farrah, Wheeler, David A., Tsavachidis, Spiridon, Armstrong, Georgina, Zhu, Dakai, Wistuba, Ignacio I., Chow, Chi-Wan B., Behrens, Carmen, Pikielny, Claudio W., Neslund-Dudas, Christine, Pinney, Susan M., Anderson, Marshall, Kupert, Elena, Bailey-Wilson, Joan, Gaba, Colette, Mandal, Diptasri, You, Ming, de Andrade, Mariza, Yang, Ping, Field, John K., Liloglou, Triantafillos, Davies, Michael, Lissowska, Jolanta, Swiatkowska, Beata, Zaridze, David, Mukeriya, Anush, Janout, Vladimir, Holcatova, Ivana, Mates, Dana, Milosavljevic, Sasa, Scelo, Ghislaine, Brennan, Paul, McKay, James, Liu, Geoffrey, Hung, Rayjean J., Christiani, David C., Schwartz, Ann G., Amos, Christopher I, Spitz, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366341/
https://ncbi.nlm.nih.gov/pubmed/29981437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2018.06.016
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