Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation

The intestinal epithelial monolayer, at the boundary between microbes and the host immune system, plays an important role in the development of inflammatory bowel disease (IBD), particularly as a target and producer of pro-inflammatory TNF. Chronic overexpression of TNF leads to IBD-like pathology o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Parker, Aimée, Vaux, Laura, Patterson, Angela M., Modasia, Amisha, Muraro, Daniele, Fletcher, Alexander G., Byrne, Helen M., Maini, Philip K., Watson, Alastair J. M., Pin, Carmen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365534/
https://ncbi.nlm.nih.gov/pubmed/30728350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1275-5
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia