Prediction of DNA Repair Inhibitor Response in Short Term Patient-Derived Ovarian Cancer Organoids

Based on genomic analysis, fifty percent of high grade serous ovarian cancers (HGSC) are predicted to have DNA repair defects. Whether this substantial subset of HGSCs actually have functional repair defects remains unknown. Here, we devise a platform for functionally profiling DNA repair in short-t...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Discov
Autors principals: Hill, Sarah J., Decker, Brennan, Roberts, Emma A., Horowitz, Neil S., Muto, Michael G., Worley, Michael J., Feltmate, Colleen M., Nucci, Marisa R., Swisher, Elizabeth M., Nguyen, Huy, Yang, Chunyu, Morizane, Ryuji, Kochupurakkal, Bose S., Do, Khanh T., Konstantinopoulos, Panagiotis A., Liu, Joyce F., Bonventre, Joseph V., Matulonis, Ursula A., Shapiro, Geoffrey I., Berkowitz, Ross S., Crum, Christopher P., D’Andrea, Alan D.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365285/
https://ncbi.nlm.nih.gov/pubmed/30213835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-0474
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars