What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies

Intravenous tranexamic acid (TXA) reduces death because of bleeding in patients with trauma and postpartum haemorrhage. However, in some settings intravenous injection is not feasible. To find different routes of administration, we first need to determine the minimal concentration of TXA in the bloo...

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Bibliographische Detailangaben
Veröffentlicht in:Blood Coagul Fibrinolysis
Hauptverfasser: Picetti, Roberto, Shakur-Still, Haleema, Medcalf, Robert L., Standing, Joseph F., Roberts, Ian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams And Wilkins 2019
Schlagworte:
Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365258/
https://ncbi.nlm.nih.gov/pubmed/30585835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000789
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