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What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies

Intravenous tranexamic acid (TXA) reduces death because of bleeding in patients with trauma and postpartum haemorrhage. However, in some settings intravenous injection is not feasible. To find different routes of administration, we first need to determine the minimal concentration of TXA in the bloo...

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Detalhes bibliográficos
Publicado no:Blood Coagul Fibrinolysis
Main Authors: Picetti, Roberto, Shakur-Still, Haleema, Medcalf, Robert L., Standing, Joseph F., Roberts, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams And Wilkins 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365258/
https://ncbi.nlm.nih.gov/pubmed/30585835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000789
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