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What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies

Intravenous tranexamic acid (TXA) reduces death because of bleeding in patients with trauma and postpartum haemorrhage. However, in some settings intravenous injection is not feasible. To find different routes of administration, we first need to determine the minimal concentration of TXA in the bloo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Coagul Fibrinolysis
Prif Awduron: Picetti, Roberto, Shakur-Still, Haleema, Medcalf, Robert L., Standing, Joseph F., Roberts, Ian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams And Wilkins 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365258/
https://ncbi.nlm.nih.gov/pubmed/30585835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000789
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