Quantitative analysis of the whole-body metabolic fate of branched chain amino acids

Elevations in branched-chain amino acids (BCAAs) associate with numerous systemic diseases, including cancer, diabetes, and heart failure. However, an integrated understanding of whole-body BCAA metabolism remains lacking. Here, we employ in vivo isotopic tracing to systemically quantify BCAA oxidat...

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Udgivet i:Cell Metab
Main Authors: Neinast, Michael D., Jang, Cholsoon, Hui, Sheng, Murashige, Danielle S., Chu, Qingwei, Morscher, Raphael J., Li, Xiaoxuan, Zhan, Le, White, Eileen, Anthony, Tracy G., Rabinowitz, Joshua D., Arany, Zoltan
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365191/
https://ncbi.nlm.nih.gov/pubmed/30449684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.10.013
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