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Comprehensive quantification of fuel use by the failing and nonfailing human heart

The heart consumes circulating nutrients to fuel lifelong contraction, but a comprehensive mapping of human cardiac fuel use is lacking. We used metabolomics on blood from artery, coronary sinus, and femoral vein in 110 patients with or without heart failure to quantify the uptake and release of 277...

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Publicat a:Science
Autors principals: Murashige, Danielle, Jang, Cholsoon, Neinast, Michael, Edwards, Jonathan J., Cowan, Alexis, Hyman, Matthew C., Rabinowitz, Joshua D., Frankel, David S., Arany, Zolt
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871704/
https://ncbi.nlm.nih.gov/pubmed/33060364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc8861
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