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Human ether-à-go-go-related gene mutation L539fs/47-hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Congenital long QT syndrome (LQTS) is a cardiac channelopathy that often results in fatal arrhythmias. LQTS mutations not only lead to abnormal myocardial electrical activities but are associated with heart contraction abnormalities, cardiomyopathy and congenital heart defects. In vivo and in vitro...

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Pubblicato in:Int J Mol Med
Autori principali: Ma, Shuting, Zhao, Yun, Cao, Miaomiao, Sun, Chaofeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365044/
https://ncbi.nlm.nih.gov/pubmed/30628647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4049
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