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The low down on sphingosine-1-phosphate lyase as a regulator of thymic egress

After undergoing positive and negative selection in the thymus, surviving mature T cells egress from the thymic parenchyma and enter the bloodstream to participate in adaptive immunity. Thymic egress requires signals mediated by sphingosine-1-phosphate (S1P), a bioactive lipid that serves as the lig...

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Publicado en:J Immunol Sci
Autor principal: Saba, Julie D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364841/
https://ncbi.nlm.nih.gov/pubmed/30740601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29245/2578-3009/2018/1.1103
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