GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump

The sodium potassium pump (Na/K-ATPase) ensures the electrochemical gradient of a cell through an energy-dependent process that consumes approximately one third of regenerated ATP. We report that the G protein-coupled receptor GPR35 interacted with the α chain of Na/K-ATPase and promotes its ion tra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Signal
Prif Awduron: Schneditz, Georg, Elias, Joshua E., Pagano, Ester, Zaeem Cader, M., Saveljeva, Svetlana, Long, Kathleen, Mukhopadhyay, Subhankar, Arasteh, Maryam, Lawley, Trevor D., Dougan, Gordon, Bassett, Andrew, Karlsen, Tom H., Kaser, Arthur, Kaneider, Nicole C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364804/
https://ncbi.nlm.nih.gov/pubmed/30600262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau9048
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