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Multiple tyrosine metabolites are GPR35 agonists

Both kynurenic acid and 2-acyl lysophosphatidic acid have been postulated to be the endogenous agonists of GPR35. However, controversy remains whether alternative endogenous agonists exist. The molecular targets accounted for many nongenomic actions of thyroid hormones are mostly unknown. Here we re...

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Autors principals: Deng, Huayun, Hu, Haibei, Fang, Ye
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330681/
https://ncbi.nlm.nih.gov/pubmed/22523636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00373
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