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Discovery of Natural Phenols as G Protein-Coupled Receptor-35 (GPR35) Agonists

[Image: see text] We report the discovery and characterization of natural phenols as G protein-coupled receptor-35 (GPR35) agonists. Pharmacological characterization using label-free dynamic mass redistribution and Tango β-arrestin translocation assays revealed that GPR35-active natural phenols are...

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Detalhes bibliográficos
Main Authors: Deng, Huayun, Hu, Haibei, Ling, Shizhang, Ferrie, Ann M., Fang, Ye
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025658/
https://ncbi.nlm.nih.gov/pubmed/24900447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2003058
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