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NPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomes
Low-density lipoprotein particles are taken up by cells and delivered to the lysosome where their cholesterol esters are cleaved off by acid lipase. The released, free cholesterol is then exported from lysosomes for cellular needs or storage. This article summarizes recent advances in our understand...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6364775/ https://ncbi.nlm.nih.gov/pubmed/30710017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.004165 |
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