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Synthetically Modified Methoxsalen for Enhanced Cytotoxicity in Light and Dark Reactions
Linear furocoumarins, also known as psoralens, are clinically useful photo-activated pharmaceuticals employed to address hyperproliferative skin diseases. Seven diverse cytotoxic pharmacophores have been synthetically attached to 8-methoxypsoralen via a 5-amino functionality. The resulting unique se...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6364570/ https://ncbi.nlm.nih.gov/pubmed/30638875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.12.048 |
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