N(ω)-NITRO-N(ω’)-SUBSTITUTED GUANIDINES: A SIMPLE CLASS OF NITRIC OXIDE SYNTHASE INHIBITORS

A series of N(ω)-nitro-N(ω’)-substituted guanidines has been prepared as potential inhibitors of the human Nitric Oxide Synthase (NOS) isoforms. The reported utility of aminoguanidine and nitroarginine in iNOS inhibition points to a potential similar utility for analogs of nitro-guanidine. The compo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guillon, Christophe D., Wisnoski, David D., Saxena, Jaya, Heindel, Ned D., Heck, Diane E., Wolff, Donald J., Laskin, Jeffrey D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209729/
https://ncbi.nlm.nih.gov/pubmed/25360396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/mri.2014.32006
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