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Recent advances in understanding RAG deficiencies

Recombination-activating genes ( RAG) 1 and RAG2 initiate the molecular processes that lead to lymphocyte receptor formation through VDJ recombination. Nonsense mutations in RAG1/ RAG2 cause the most profound immunodeficiency syndrome, severe combined immunodeficiency (SCID). Other severe and less-s...

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Detalles Bibliográficos
Publicado en:F1000Res
Autor Principal: Gennery, Andrew
Formato: Artigo
Idioma:Inglês
Publicado: F1000 Research Limited 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364374/
https://ncbi.nlm.nih.gov/pubmed/30800289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.17056.1
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