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Recent advances in understanding RAG deficiencies
Recombination-activating genes ( RAG) 1 and RAG2 initiate the molecular processes that lead to lymphocyte receptor formation through VDJ recombination. Nonsense mutations in RAG1/ RAG2 cause the most profound immunodeficiency syndrome, severe combined immunodeficiency (SCID). Other severe and less-s...
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| Publicado no: | F1000Res |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
F1000 Research Limited
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6364374/ https://ncbi.nlm.nih.gov/pubmed/30800289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.17056.1 |
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