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Design, display and immunogenicity of HIV1 gp120 fragment immunogens on virus-like particles
The broadly neutralizing antibody against HIV-1, bl2, binds to the CD4 binding site (CD4bs) on the outer domain (OD) of the gp120 subunit of HIV-1 Env. We have previously reported the design of an E.coli expressed fragment of HIV-1 gp120, b122a, containing about 70% of the b12 epitope with the idea...
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| Publicado no: | Vaccine |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6364316/ https://ncbi.nlm.nih.gov/pubmed/30220462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.07.032 |
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