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The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy

Patients undergoing surgical resection of primary breast tumors confront a risk for metastatic recurrence that peaks sharply 12 to 18 months after surgery. The cause of early metastatic relapse in breast cancer has long been debated, with many ascribing these relapses to the natural progression of t...

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Detalles Bibliográficos
Publicado en:Sci Transl Med
Main Authors: Krall, Jordan A., Reinhardt, Ferenc, Mercury, Oblaise A., Pattabiraman, Diwakar R., Brooks, Mary W., Dougan, Michael, Lambert, Arthur W., Bierie, Brian, Ploegh, Hidde L., Dougan, Stephanie K., Weinberg, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364295/
https://ncbi.nlm.nih.gov/pubmed/29643230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan3464
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