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Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability
The epithelial-to-mesenchymal transition (EMT) enables carcinoma cells to acquire malignancy-associated traits and properties of tumor-initiating cells (TICs). TICs have emerged in recent years as important targets for cancer therapy owing to their ability to drive clinical relapse and enable metast...
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| Wydane w: | Science |
|---|---|
| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131720/ https://ncbi.nlm.nih.gov/pubmed/26941323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad3680 |
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