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The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions

Disseminated cancer cells that have extravasated into the tissue parenchyma must interact productively with its extracellular matrix (ECM) components in order to survive, proliferate and form macroscopic metastases. The biochemical and cell-biological mechanisms enabling this interaction remain poor...

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Hlavní autoři: Shibue, Tsukasa, Brooks, Mary W., Inan, M. Fatih, Reinhardt, Ferenc, Weinberg, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418422/
https://ncbi.nlm.nih.gov/pubmed/22609699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0239
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