An HIV-1 Broadly Neutralizing Antibody from a Clade C-Infected Pediatric Elite Neutralizer Potently Neutralizes the Contemporaneous and Autologous Evolving Viruses

Broadly neutralizing antibodies (bNAbs) have demonstrated protective effects against HIV-1 in primate studies and recent human clinical trials. Elite neutralizers are potential candidates for isolation of HIV-1 bNAbs. The coexistence of bNAbs such as BG18 with neutralization-susceptible autologous v...

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Veröffentlicht in:J Virol
Hauptverfasser: Kumar, Sanjeev, Panda, Harekrushna, Makhdoomi, Muzamil Ashraf, Mishra, Nitesh, Safdari, Haaris Ahsan, Chawla, Himanshi, Aggarwal, Heena, Reddy, Elluri Seetharami, Lodha, Rakesh, Kumar Kabra, Sushil, Chandele, Anmol, Dutta, Somnath, Luthra, Kalpana
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364018/
https://ncbi.nlm.nih.gov/pubmed/30429339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01495-18
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