Viral Characteristics Associated with Maintenance of Elite Neutralizing Activity in Chronically HIV-1 Clade C-Infected Monozygotic Pediatric Twins

Broad and potent neutralizing antibodies (bnAbs) with multiple epitope specificities evolve in HIV-1-infected children. Herein, we studied two antiretroviral-naive chronically HIV-1 clade C-infected monozygotic pediatric twins, AIIMS_329 and AIIMS_330, with potent plasma bnAbs. Elite plasma neutrali...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mishra, Nitesh, Makhdoomi, Muzamil Ashraf, Sharma, Shaifali, Kumar, Sanjeev, Dobhal, Ayushman, Kumar, Deepshikha, Chawla, Himanshi, Singh, Ravinder, Kanga, Uma, Das, Bimal Kumar, Lodha, Rakesh, Kabra, Sushil K., Luthra, Kalpana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694815/
https://ncbi.nlm.nih.gov/pubmed/31217240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00654-19
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