Hepatitis C Virus Escape Studies of Human Antibody AR3A Reveal a High Barrier to Resistance and Novel Insights on Viral Antibody Evasion Mechanisms

Yearly, ∼2 million people become hepatitis C virus (HCV) infected, resulting in an elevated lifetime risk for severe liver-related chronic illnesses. Characterizing epitopes of broadly neutralizing antibodies (NAbs), such as AR3A, is critical to guide vaccine development. Previously identified alani...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Velázquez-Moctezuma, Rodrigo, Galli, Andrea, Law, Mansun, Bukh, Jens, Prentoe, Jannick
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364003/
https://ncbi.nlm.nih.gov/pubmed/30487284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01909-18
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