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cAMP binds to closed, inactivated, and open sea urchin HCN channels in a state-dependent manner
Hyperpolarization-activated cyclic-nucleotide–modulated (HCN) channels are nonselective cation channels that regulate electrical activity in the heart and brain. Previous studies of mouse HCN2 (mHCN2) channels have shown that cAMP binds preferentially to and stabilizes these channels in the open sta...
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| Publicado no: | J Gen Physiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6363418/ https://ncbi.nlm.nih.gov/pubmed/30541772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812019 |
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