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New Insights into the Mechanism of NO(3)(-) Selectivity in the Human Kidney Chloride Channel ClC-Ka and the CLC Protein Family

BACKGROUND: The mechanism of anion selectivity in the human kidney chloride channels ClC-Ka and ClC-Kb is unknown. However, it has been thought to be very similar to that of other channels and antiporters of the CLC protein family, and to rely on anions interacting with a conserved Ser residue (Ser(...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Principais autores: Lagostena, Laura, Zifarelli, Giovanni, Picollo, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362620/
https://ncbi.nlm.nih.gov/pubmed/30635372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018060593
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