Role of PKC in the Regulation of the Human Kidney Chloride Channel ClC-Ka

The physiological role of the renal ClC-Ka/ClC-K1 channels is to confer a high Cl(-) permeability to the thin Ascending Limb of Henle (tAL), which in turn is essential for establishing the high osmolarity of the renal medulla that drives water reabsorption from collecting ducts. Here, we investigate...

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Published in:Sci Rep
Main Authors: Gerbino, Andrea, De Zio, Roberta, Russo, Daniela, Milella, Luigi, Milano, Serena, Procino, Giuseppe, Pusch, Michael, Svelto, Maria, Carmosino, Monica
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314819/
https://ncbi.nlm.nih.gov/pubmed/32581267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67219-8
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