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Chromosome alignment maintenance requires the MAP RECQL4, mutated in the Rothmund–Thomson syndrome
RecQ-like helicase 4 (RECQL4) is mutated in patients suffering from the Rothmund–Thomson syndrome, a genetic disease characterized by premature aging, skeletal malformations, and high cancer susceptibility. Known roles of RECQL4 in DNA replication and repair provide a possible explanation of chromos...
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| Publicado no: | Life Sci Alliance |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6362308/ https://ncbi.nlm.nih.gov/pubmed/30718377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800120 |
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