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Pigment epithelium-derived factor mediates retinal ganglion cell neuroprotection by suppression of caspase-2
Retinal ganglion cells (RGCs) undergo rapid cell death by apoptosis after injury but can be rescued by suppression of caspase-2 (CASP2) using an siRNA to CASP2 (siCASP2). Pigment epithelium-derived factor (PEDF), has neuroprotective and anti-angiogenic functions and protects RGC from death. The purp...
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| Udgivet i: | Cell Death Dis |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6362048/ https://ncbi.nlm.nih.gov/pubmed/30718480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1379-6 |
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