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Eye drop delivery of pigment epithelium-derived factor-34 promotes retinal ganglion cell neuroprotection and axon regeneration

Axotomised retinal ganglion cells (RGCs) die rapidly by apoptosis and fail to regenerate because of the limited availability of neurotrophic factors and a lack of axogenic stimuli. However, we have recently showed that pigment epithelium-derived factor (PEDF) promotes RGC survival and axon regenerat...

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Detalhes bibliográficos
Publicado no:Mol Cell Neurosci
Main Authors: Vigneswara, Vasanthy, Esmaeili, Maryam, Deer, Louise, Berry, Martin, Logan, Ann, Ahmed, Zubair
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604765/
https://ncbi.nlm.nih.gov/pubmed/26260110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2015.08.001
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