Pharmacological Inhibition of Caspase-2 Protects Axotomised Retinal Ganglion Cells from Apoptosis in Adult Rats

Severing the axons of retinal ganglion cells (RGC) by crushing the optic nerve (ONC) causes the majority of RGC to degenerate and die, primarily by apoptosis. We showed recently that after ONC in adult rats, caspase-2 activation occurred specifically in RGC while no localisation of caspase-3 was obs...

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Detaylı Bibliyografya
Asıl Yazarlar: Vigneswara, Vasanthy, Berry, Martin, Logan, Ann, Ahmed, Zubair
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532067/
https://ncbi.nlm.nih.gov/pubmed/23285297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053473
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