miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling

NF-κB functions as modulator of T cell receptor-mediated signaling and transcriptional regulator of miR-34a. Our in silico analysis revealed that miR-34a impacts the NF-κB signalosome with miR-34a binding sites in 14 key members of the NF-κB signaling pathway. Functional analysis identified five tar...

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Publicat a:Cell Death Dis
Autors principals: Hart, Martin, Walch-Rückheim, Barbara, Friedmann, Kim S., Rheinheimer, Stefanie, Tänzer, Tanja, Glombitza, Birgit, Sester, Martina, Lenhof, Hans-Peter, Hoth, Markus, Schwarz, Eva C., Keller, Andreas, Meese, Eckart
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362007/
https://ncbi.nlm.nih.gov/pubmed/30718475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1295-1
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