Induction of the Endoplasmic-Reticulum-Stress Response: MicroRNA-34a Targeting of the IRE1α-Branch

Neurodegenerative disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) are characterized by the accumulation of misfolded proteins in the endoplasmic reticulum (ER) and the unfolded protein response (UPR). Modulating the UPR is one of the major challenges to counteract the develop...

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Udgivet i:Cells
Main Authors: Krammes, Lena, Hart, Martin, Rheinheimer, Stefanie, Diener, Caroline, Menegatti, Jennifer, Grässer, Friedrich, Keller, Andreas, Meese, Eckart
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348704/
https://ncbi.nlm.nih.gov/pubmed/32531952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061442
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