Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity

Antimicrobial peptides (AMPs) are a potential source of new molecules to counter the increase in antimicrobial resistant infections but a better understanding of their properties is required to understand their native function and for effective translation as therapeutics. Details of the mechanism o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Manzo, Giorgia, Ferguson, Philip M., Gustilo, V. Benjamin, Hind, Charlotte K., Clifford, Melanie, Bui, Tam T., Drake, Alex F., Atkinson, R. Andrew, Sutton, J. Mark, Batoni, Giovanna, Lorenz, Christian D., Phoenix, David A., Mason, A. James
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362004/
https://ncbi.nlm.nih.gov/pubmed/30718667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37630-3
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