Small Molecule BKM1972 Inhibits Human Prostate Cancer Growth and Overcomes Docetaxel Resistance in Intraosseous Models

Bone metastasis is a major cause of prostate cancer (PCa) mortality. Although docetaxel chemotherapy initially extends patients’ survival, in most cases PCa becomes chemoresistant and eventually progresses without a cure. In this study, we developed a novel small-molecule compound BKM1972, which exh...

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Detaylı Bibliyografya
Yayımlandı:Cancer Lett
Asıl Yazarlar: Chen, Yanhua, Gera, Lajos, Zhang, Shumin, Li, Xin, Yang, Yang, Mamouni, Kenza, Wu, Alyssa Y., Liu, HongYan, Kucuk, Omer, Wu, Daqing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361683/
https://ncbi.nlm.nih.gov/pubmed/30660650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.01.010
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