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Inhibition of skeletal growth of human prostate cancer by the combination of docetaxel and BKM1644: an aminobisphosphonate derivative

Bone metastasis is a major cause of prostate cancer (PCa) morbidity and mortality. Despite some success in transiently controlling clinical symptoms with docetaxel-based therapy, PCa patients become docetaxel-resistant and inevitably progress with no cure. We synthesized an acyl-tyrosine bisphosphon...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Shumin, Gera, Lajos, Mamouni, Kenza, Li, Xin, Chen, Zhengjia, Kucuk, Omer, Wu, Daqing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053666/
https://ncbi.nlm.nih.gov/pubmed/27050371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8481
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