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Potent antiproliferative effect of fatty‐acid derivative AIC‐47 on leukemic mice harboring BCR‐ABL mutation

Therapy based on targeted inhibition of BCR‐ABL tyrosine kinase has greatly improved the prognosis for patients with Philadelphia chromosome (Ph)‐positive leukemia and tyrosine kinase inhibitors (TKI) have become standard therapy. However, some patients acquire resistance to TKI that is frequently a...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Shinohara, Haruka, Sugito, Nobuhiko, Kuranaga, Yuki, Heishima, Kazuki, Minami, Yosuke, Naoe, Tomoki, Akao, Yukihiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361563/
https://ncbi.nlm.nih.gov/pubmed/30548479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13913
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