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Potent antiproliferative effect of fatty‐acid derivative AIC‐47 on leukemic mice harboring BCR‐ABL mutation

Therapy based on targeted inhibition of BCR‐ABL tyrosine kinase has greatly improved the prognosis for patients with Philadelphia chromosome (Ph)‐positive leukemia and tyrosine kinase inhibitors (TKI) have become standard therapy. However, some patients acquire resistance to TKI that is frequently a...

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Dades bibliogràfiques
Publicat a:Cancer Sci
Autors principals: Shinohara, Haruka, Sugito, Nobuhiko, Kuranaga, Yuki, Heishima, Kazuki, Minami, Yosuke, Naoe, Tomoki, Akao, Yukihiro
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361563/
https://ncbi.nlm.nih.gov/pubmed/30548479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13913
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