Caricamento...
New Therapeutic Targets for Alpha-1 Antitrypsin Deficiency
Alpha-1antitrypsin deficiency (AATD) results from the intracellular polymerization and retention of mutant alpha-1antitrypsin (AAT) within the endoplasmic reticulum of hepatocytes. This causes cirrhosis whilst the deficiency of circulating AAT predisposes to early onset emphysema. This is an excitin...
Salvato in:
| Pubblicato in: | Chronic Obstr Pulm Dis |
|---|---|
| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
COPD Foundation Inc
2018
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6361470/ https://ncbi.nlm.nih.gov/pubmed/30723781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15326/jcopdf.5.4.2017.0165 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|