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CTCF sites display cell cycle–dependent dynamics in factor binding and nucleosome positioning

CCCTC-binding factor (CTCF) plays a key role in the formation of topologically associating domains (TADs) and loops in interphase. During mitosis TADs are absent, but how TAD formation is dynamically controlled during the cell cycle is not known. Several contradicting observations have been made reg...

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Библиографические подробности
Опубликовано в: :Genome Res
Главные авторы: Oomen, Marlies E., Hansen, Anders S., Liu, Yu, Darzacq, Xavier, Dekker, Job
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360813/
https://ncbi.nlm.nih.gov/pubmed/30655336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.241547.118
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