Isoliquiritigenin Induces Mitochondrial Dysfunction and Apoptosis by Inhibiting mitoNEET in a Reactive Oxygen Species-Dependent Manner in A375 Human Melanoma Cells

The mitochondrial protein mitoNEET is a type of iron-sulfur protein localized to the outer membrane of mitochondria and is involved in a variety of human pathologies including cystic fibrosis, diabetes, muscle atrophy, and neurodegeneration. In the current study, we found that isoliquiritigenin (ISL...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Chen, Xiao-Yu, Ren, Huan-Huan, Wang, Dan, Chen, Ying, Qu, Chuan-Jun, Pan, Zhao-Hai, Liu, Xiao-Na, Hao, Wen-Jin, Xu, Wen-Juan, Wang, Ke-Jun, Li, De-Fang, Zheng, Qiu-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360568/
https://ncbi.nlm.nih.gov/pubmed/30805086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9817576
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