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Polygenic risk score increases schizophrenia liability through cognition-relevant pathways

Cognitive deficit is thought to represent, at least in part, genetic mechanisms of risk for schizophrenia, with recent evidence from statistical modelling of twin data suggesting direct causality from the former to the latter. However, earlier evidence was based on inferences from twin not molecular...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Brain
Κύριοι συγγραφείς: Toulopoulou, Timothea, Zhang, Xiaowei, Cherny, Stacey, Dickinson, Dwight, Berman, Karen F, Straub, Richard E, Sham, Pak, Weinberger, Daniel R
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359897/
https://ncbi.nlm.nih.gov/pubmed/30535067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy279
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