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Polygenic risk score increases schizophrenia liability through cognition-relevant pathways

Cognitive deficit is thought to represent, at least in part, genetic mechanisms of risk for schizophrenia, with recent evidence from statistical modelling of twin data suggesting direct causality from the former to the latter. However, earlier evidence was based on inferences from twin not molecular...

詳細記述

保存先:
書誌詳細
出版年:Brain
主要な著者: Toulopoulou, Timothea, Zhang, Xiaowei, Cherny, Stacey, Dickinson, Dwight, Berman, Karen F, Straub, Richard E, Sham, Pak, Weinberger, Daniel R
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359897/
https://ncbi.nlm.nih.gov/pubmed/30535067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy279
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