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Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph
BACKGROUND: Recent Genome Wide Association Studies (GWAS) have identified novel rare coding variants in immune genes associated with late onset Alzheimer’s disease (LOAD). Amongst these, a polymorphism in phospholipase C-gamma 2 (PLCG2) P522R has been reported to be protective against LOAD. PLC enzy...
Gorde:
| Argitaratua izan da: | Alzheimers Res Ther |
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| Egile Nagusiak: | , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
BioMed Central
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6359863/ https://ncbi.nlm.nih.gov/pubmed/30711010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0469-0 |
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