Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph

BACKGROUND: Recent Genome Wide Association Studies (GWAS) have identified novel rare coding variants in immune genes associated with late onset Alzheimer’s disease (LOAD). Amongst these, a polymorphism in phospholipase C-gamma 2 (PLCG2) P522R has been reported to be protective against LOAD. PLC enzy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Alzheimers Res Ther
Egile Nagusiak: Magno, Lorenza, Lessard, Christian B., Martins, Marta, Lang, Verena, Cruz, Pedro, Asi, Yasmine, Katan, Matilda, Bilsland, Jamie, Lashley, Tammaryn, Chakrabarty, Paramita, Golde, Todd E., Whiting, Paul J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359863/
https://ncbi.nlm.nih.gov/pubmed/30711010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0469-0
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak