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Direct Synthesis of Phosphonates and α-Amino-phosphonates from 1,3-Benzoxazines

A straightforward and novel method for transformation of readily available 1,3-benzoxazines to secondary phosphonates and α-aminophosphonates using boron trifluoride etherate as catalyst is developed. The formation of phosphonates proceeds through ortho-quinone methide (o-QM) generated in situ, foll...

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Bibliographic Details
Published in:Molecules
Main Authors: Salgado-Escobar, Oscar, Hernández-Guadarrama, Alexis, Romero-Estudillo, Ivan, Linzaga-Elizalde, Irma
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359518/
https://ncbi.nlm.nih.gov/pubmed/30650579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24020294
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