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Synthesis of C-glycosyl phosphonate derivatives of 4-amino-4-deoxy-α-ʟ-arabinose

The incorporation of basic substituents into the structurally conserved domains of cell wall lipopolysaccharides has been identified as a major mechanism contributing to antimicrobial resistance of Gram-negative pathogenic bacteria. Inhibition of the corresponding enzymatic steps, specifically the t...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Kerner, Lukáš, Kosma, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964659/
https://ncbi.nlm.nih.gov/pubmed/31976011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.2
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